Complementary evolution of coding and noncoding sequence underlies . . . To find the genetic basis of reduced hair quantity, we used our evolutionary-rates-based method, RERconverge, to identify coding and noncoding sequences that evolve at significantly different rates in so-called hairless mammals compared to hairy mammals
Complementary evolution of coding and noncoding sequence underlies . . . Using RERconverge, we performed an unbiased, genome-wide scan over 62 mammal species using 19,149 genes and 343,598 conserved noncoding regions to find genetic elements that evolve at significantly different rates in hairless mammals compared to hairy mammals
Complementary evolution of coding and noncoding sequence . . . Using RERconverge, we performed an unbiased, genome-wide scan over 62 mammal species using 19,149 genes and 343,598 conserved noncoding regions to find genetic elements that evolve at significantly different rates in hairless mammals compared to hairy mammals
Complementary evolution of coding and noncoding sequence underlies . . . To find the genetic basis of reduced hair quantity, we used our evolutionary-rates-based method, RERconverge, to identify coding and noncoding sequences that evolve at significantly different rates in so-called hairless mammals compared to hairy mammals
Complementary evolution of coding and noncoding sequence underlies . . . ut several mammals, such as whales, naked mole- rats, and humans, have notably less hair To find the genetic basis of reduced hair quan-tity, we used our evolutionary- rates- based method, RERconverge, to identify coding and noncoding sequences that evolve
Complementary evolution of coding and noncoding sequence underlies . . . 25 evolutionary rate shifts in nearby noncoding regions Conversely, accelerated noncoding regions 26 are most strongly enriched near regulatory hair-related genes and microRNAs, such as mir205, 27 ELF3, and FOXC1, that themselves do not show rate shifts in their protein-coding sequences
Complementary evolution of coding and noncoding sequence underlies . . . To find the genetic basis of reduced hair quantity, we used our evolutionary-rates-based method, RERconverge, to identify coding and noncoding sequences that evolve at significantly different rates in so-called hairless mammals compared to hairy mammals
eLife To find the genetic basis of reduced hair quantity, we used our evolutionary-rates-based method, RERconverge, to identify coding and noncoding sequences that evolve at significantly different rates in so-called hairless mammals compared to hairy mammals
